Genetics & Mapping

A Toolbook & Hypercard Stack Simulation

M. Watson and J. Evans

Department of Biological Sciences

University of Durham

These programs were developed for use by biology undergraduates studying genetics. The original program was developed on the Macintosh using Hypercard stacks and subsequently converted to run on Windows based PCs using Asymetrix Toolbook.

The first part of the program, Genetics, takes undergraduates through the basic principles of Mendelian genetics, monohybrid and dihybrid crosses, and the derivation of the resultant phenotypes. The basics of meiosis are outlined and how this relates to the generation of random assortment. Variations on the classic 9:3:3:1 ratios are included to show how different phenotypic ratios are derived under conditions of gene interaction. The second part of the program, Mapping, is a short tutorial on how to perform three factor crosses, determine gene order, distance and the effects of interference.

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